SpectraComp®
SpectraComp® Controls are precision engineered single stain cell mimics designed to optimize spectral unmixing and compensation in multiparameter flow cytometry workflows. These controls mimic the staining performance of real cells and provide positive and negative fluorescence peaks after staining with fluorescently conjugated antibodies. Each control captures antibodies from mouse, rat and hamster sources, supporting broad panel compatibility and diverse fluorophore selections.
With high fluorescence response and cell like autofluorescence, SpectraComp delivers superior signal to noise resolution and reduces errors associated with spectral overlap. Its consistent fluorescence intensity and physiologically relevant scatter characteristics outperform traditional polystyrene based beads while preserving the behavior of cell based controls. SpectraComp is suitable for spectral unmixing or conventional compensation and is supplied as a single vial containing both positive and negative capture mimics for streamlined workflows.
These controls require no special handling or safety precautions and have been validated on analytical flow cytometers for dependable performance in daily QC, assay development and high parameter panel design.
Benefits:
- Unparalleled high fluorescence response (greater than 10e5 MFI on most bright fluorochrome)
- Conveniently works with multiple species of antibodies: mouse, rat, and hamster
- Exceptional performance in spectral analysis and unmixing
- Compatible with violet and UV fluorochromes
- Cell-like autofluorescence for superior signal-to-noise resolution
Resources:
Poster:
Spectral Cytometry Reference Controls: The Search for the Perfect Particle
Publication:
